Surface display of functional proteins in a broad range of gram negative bacteria
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
Jun 16, 2020
Grant Date -
Apr 21, 2016
app pub date -
Jun 4, 2014
filing date -
Mar 13, 2013
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
The present invention relates to a method for the surface display of a recombinant polypeptide on the surface of a host cell, said method comprising the steps: (a) providing a host cell transformed with a nucleic acid fusion operatively linked with an expression control sequence, said nucleic acid fusion comprising: (i) a portion encoding a signal peptide, (ii) a portion encoding the recombinant polypeptide to be displayed, (iii) a portion encoding a transmembrane linker, and (iv) a portion encoding the trans porter domain of an EhaA protein, and (b) culturing the host cell under conditions wherein the nucleic acid fusion is expressed and the expression product comprising the recombinant polypeptide is displayed on the surface of the host cell.
First Claim
Other Claims data not available
Family
International Classification(s)
Cited Art Landscape
Patent Citation Ranking
- 0 Citation Count
- C12N Class
- 0 % this patent is cited more than
- 5 Age
Maintenance Fees
| Fee | Large entity fee | small entity fee | micro entity fee | due date |
|---|---|---|---|---|
| 7.5 Year Payment | $3600.00 | $1800.00 | $900.00 | Dec 16, 2027 |
| 11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | Dec 16, 2031 |
