METHODS FOR DETECTING A MYCOBACTERIUM TUBERCULOSIS INFECTION
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United States of America Patent
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Sep 16, 2015
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Nov 20, 2009
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Abstract
Methods for detecting an infection with Mtb in a subject are disclosed. The methods include detecting the presence of CD8+ T cells that specifically recognize an Mtb polypeptide. The methods include in vitro assays for detecting the presence of CD8+ T cells in a biological sample, and in vivo assays that detect a delayed type hypersensitivity reaction. The methods also include detecting Mtb polypeptides and polynucleotides.
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