ORGANOIDS COMPRISING ISOLATED RENAL CELLS AND USE THEREOF
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United States of America Patent
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Apr 14, 2016
app pub date -
May 8, 2014
filing date -
May 8, 2013
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Abstract
Described herein are organoids comprising admixtures of selected bioactive primary renal cells and a bioactive cell population, e.g., an endothelial cell populations, e.g. HUVEC cells, and methods of treating a subject in need thereof with such organoids. Further, the isolated renal cells, which may include tubular and erythropoietin {EPO}-producing kidney cell populations, and/or the endothelial cell populations may be of autologous, syngeneic, allogeneic or xenogeneic origin, or any combination thereof. Further provided are methods of treating a subject in need with the organoids.
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