PC33718E

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20160096898A1
SERIAL NO

14864750

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides antagonizing antibodies, antigen-binding portions thereof, and aptamers that bind to proprotein convertase subtilisin kexin type 9 (PCSK9). Also provided are antibodies directed to peptides, in which the antibodies bind to PCSK9. The invention further provides a method of obtaining such antibodies and antibody-encoding nucleic acid. The invention further relates to therapeutic methods for use of these antibodies and antigen-binding portions thereof to reduce LDL-cholesterol levels and/or for the treatment and/or prevention of cardiovascular disease, including treatment of hypercholesterolemia.

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Patent Owner(s)

Patent OwnerAddress
PFIZER INCNEW YORK UNITED STATES NEW YORK

International Classification(s)

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  • 2015 Application Filing Year
  • C07K Class
  • 5128 Applications Filed
  • 3629 Patents Issued To-Date
  • 70.77 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances201520162017201820192020202120222023202420250255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
ABDICHE, Yasmina Noubia Mountain View, US 31 1194
CHAPARRO, RIGGERS Javier Fernando San Mateo, US 33 868
GOMES, Bruce Charles Ashburnham, US 10 678
HAWKINS, Julie Jia Li Weston, US 11 531
LIANG, Hong Hillsborough, US 53 901
PONS, Jaume San Francisco, US 98 2170
QIU, Xiayang Mystic, US 21 198
STROP, Pavel San Mateo, US 43 756
WANG, Yuli San Diego, US 53 688

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  • C07K Class
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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges246719192104419114211201 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 90100 +0200400600800100012001400160018002000220024002600

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