METHOD FOR A CELL-BASED DRUG SCREENING ASSAY AND THE USE THEREOF
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Mar 17, 2016
app pub date -
Apr 22, 2014
filing date -
Apr 25, 2013
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Abstract
A cell-based drug screening assay comprising the steps of: (i) culturing a cell population in a culturing environment, (ii) defining at least two monitoring points in time in dependency of at least one of the cell types, physiological characteristics of the cells, physiological characteristics of formed-tissue, the mode of action of a drug substance and the culturing environment, (iii) applying drug substances to the cultured cells at least at one treatment point in time, (iv) monitoring of the effect of the drug substance on cells or formed tissues at least at the two monitoring points in time.
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