Compositions and Methods for Controlled Release of Agents

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United States of America Patent

APP PUB NO 20160075776A1
SERIAL NO

14855946

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Abstract

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This invention discloses reservoirs, such as implants for delivering therapeutic agents, particularly large molecules such as proteins and antibodies. The reservoirs may comprise a porous silicon-based carrier material impregnated with the therapeutic agent. The reservoir may be used in vitro or in vivo to maintain an equilibrium concentration of a therapeutic agent over an intended period of time such as over multiple days, weeks, months, or years. Additionally, the reservoir may be reloaded with additional therapeutic agent. These reservoirs may be used for treating or preventing conditions of a subject such as chronic diseases.

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PSIVIDA US INC400 PLEASANT STREET WATERTOWN MA 02472

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  • 2015 Application Filing Year
  • A61K Class
  • 16157 Applications Filed
  • 11882 Patents Issued To-Date
  • 73.55 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances201520162017201820192020202120222023202420250255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ashton, Paul Newton, US 98 8158
Canham, Leigh T Malvern, GB 46 1136
Guo, Hong Wayland, US 77 2315
Nadarassan, Dinesh Worcestershire, GB 1 0

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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges6209860894426710349291291182201 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +0500100015002000250030003500400045005000550060006500700075008000850090009500

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