MODULATION OF REGULATORY T CELL FUNCTION VIA PROTEIN KINASE C-eta
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Mar 17, 2016
app pub date -
Apr 30, 2014
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Apr 30, 2013
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Abstract
Compounds, uses and methods for modulating an immune response are provided. In particular, modulating the interaction of PKCη with CTLA-4 can modulate an immune response. For example, modulating activity or expression of PKCη, and/or modulating activity or expression of CTLA-4, can be used to modulate interaction of PKCη with CTLA-4, thereby modulating an immune response.
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