TUMOR SPECIFIC ANITBODY CONJUGATES AND USES THEREFOR
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United States of America Patent
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app pub date -
Sep 4, 2015
filing date -
Sep 5, 2014
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Abstract
Provided are isolated antibodies, and fragments and derivatives thereof, which bind to tumor antigens. Provided are antibody/nanoparticle conjugates. Also provided are compositions and delivery agents that include the disclosed antibodies, conjugates, fragments and derivatives thereof; cells that produce the same; methods for producing the same; methods of using the same for detecting, targeting, and/or treating tumors and/or metastatic cells derived therefrom and/or tumor stem cells; and methods for predicting the recurrence of cancer in a subject.
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