STABILIZED COMPOSITION FOR TREATING PSORIASIS
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United States of America Patent
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Issued Date -
Mar 10, 2016
app pub date -
Nov 13, 2015
filing date -
Oct 3, 2008
priority date (Note) -
Abandoned
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Abstract
A storage stable ointment of the present invention comprises a vitamin D compound, a corticosteroid, and an N,N-di(C1-C8) alkylamino substituted, (C4-C18) alkyl (C2-C18) carboxylic ester a (C1-C4)-alkyl (C8-C22) carboxylic ester in a petrolatum ointment base, and optionally containing mineral oil and/or tocopherol. Preferably, the vitamin D compound is calcipotriene, the corticosteroid is selected from the group consisting of clobetasol propionate and betamethasone dipropionate, and the N,N-di(C1-C8) alkylamino substituted, (C4-C18) alkyl (C2-C18) carboxylic ester comprises dodecyl 2-(N,N-dimethylamino)-propionate (DDAIP).
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