COMPOSITIONS AND METHODS FOR DETECTION AND TREATMENT OF HEPATOCELLULAR CARCINOMA
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Mar 3, 2016
app pub date -
Apr 14, 2014
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Apr 12, 2013
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Disclosed herein are compositions and methods to treat hepatocellular carcinoma. In one embodiment, a method of treating a subject with hepatocellular carcinoma comprises administering a therapeutically effective amount of an immunoconjugate (VB4-845) comprising an antibody conjugated to an effector molecule, and wherein the antibody recognizes epithelial cell adhesion molecule (Ep-CAM). The effector molecule may be Pseudomonas exotoxin A. In some embodiments, the immunoconjugate may be co-administered, concurrently administered, or sequentially administered with one or more other anticancer agents.
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