OPIOID AGONIST/ANTAGONIST COMBINATIONS

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United States of America Patent

APP PUB NO 20160051539A1
SERIAL NO

14931205

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention is directed in part to oral dosage forms comprising a combination of an orally analgesically effective amount of an opioid agonist and an orally active opioid antagonist, the opioid antagonist being included in a ratio to the opioid agonist to provide a combination product which is analgesically effective when the combination is administered orally, but which is aversive in a physically dependent subject. Preferably, the amount of opioid antagonist included in the combination product provides at least a mildly negative, “aversive” experience in physically dependent addicts (e.g., precipitated abstinence syndrome).

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Patent Owner(s)

Patent OwnerAddress
PURDUE PHARMA L PONE STAMFORD FORUM 201 TRESSER BOULEVARD STAMFORD CT 06901

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Colucci, Robert D Newton, US 21 2575
KAIKO, Robert F Weston, US 47 4159

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