TRANSGENIC NON-HUMAN ORGANISMS WITH NON-FUNCTIONAL TSPO GENES

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United States of America Patent

APP PUB NO 20160050895A1
SERIAL NO

14775650

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to transgenic animal models. Specifically, the present invention relates to transgenic animal models for applications associated with TSPO-related normal physiology, diseases and disorders. The present invention features a transgenic nonhuman animal comprising cells with at least one copy of a non-functional, endogenous TSPO gene. Also disclosed are compounds for investigating or modulating TSPO-related functions.

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Patent Owner(s)

Patent OwnerAddress
THE UNIVERSITY OF SYDNEYPARRAMATTA ROAD THE UNIVERSITY OF SYDNEY NEW SOUTH WALES 2006 AUSTRALIA
AUSTRALIAN NUCLEAR SCIENCE AND TECHNOLOGY ORGANIZATIONNEW ILLAWARRA ROAD LUCAS HEIGHTS NEW SOUTH WALES 2234

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
BANATI, Richard Grays Point, AU 1 0
LIU, Guo Jun Penshurst, AU 1 0
MIDDLETON, Ryan Leichhardt, AU 3 28

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