NRF2 SMALL MOLECULE INHIBITORS FOR CANCER THERAPY
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United States of America Patent
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Issued Date -
Feb 18, 2016
app pub date -
Mar 17, 2014
filing date -
Mar 15, 2013
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Abstract
Small molecule inhibitors of Nrf2 and methods of their use are provided for treating or preventing a disease, disorder or condition associated with an Nrf2-regulated pathway. The compound can be administered as a single agent or can be administered to enhance the efficacy of a chemotherapeutic drug and/or radiation therapy.
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