Detection of Non-Nucleic Acid Analytes Using Strand Displacement Exchange Reactions
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Feb 4, 2016
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Sep 11, 2013
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Sep 11, 2012
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Abstract
The present invention relates to an analyte detection system for detecting analytes different from DNA and RNA. The system comprises a set of oligonucleotides which may hybridize to each other in specific ways and is able to generate a signal based on the specific hybridization events. The system relies on changes in the hybridization equilibrium between the oligonucleotides in the presence of an analyte or analytes, which results in a change in signal.
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