Ribosomal ribonucleic acid hybridization for organism identification

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United States of America Patent

PATENT NO 11441196
APP PUB NO 20160032364A1
SERIAL NO

14775296

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Abstract

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The present disclosure relates to method of distinguishing between two or more species of one or more organisms in a sample, by contacting a biological sample comprising ribosomal ribonucleic acid (rRNA) with a set of antisense probes, wherein the set of probes contains at least one detectable probe that is specific for a target rRNA sequence of each species to be tested, and wherein the individual probes specific for each species comprises less than about 85% sequence identity; and, detecting hybridization between one or more of the probes and the rRNA, thereby distinguishing between two or more species in a sample.

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Patent Owner(s)

Patent OwnerAddress
THE GENERAL HOSPITAL CORPORATION55 FRUIT STREET BOSTON MA 02114
THE BROAD INSTITUTE INC415 MAIN STREET CAMBRIDGE MA 02142

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bhattacharyya, Roby Cambridge, US 10 58
Hung, Deborah Lexington, US 28 79
Livny, Jonathan Cambridge, US 3 15

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