Stabilized Formulations Containing Anti-PCSK9 Antibodies

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United States of America Patent

APP PUB NO 20160032015A1
SERIAL NO

14918109

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides pharmaceutical formulations comprising a human antibody that specifically binds to human proprotein convertase subtilisin/kexin type 9 (PCSK9). The formulations may contain, in addition to an anti-PCSK9 antibody, at least one amino acid, at least one sugar, or at least one non-ionic surfactant. The pharmaceutical formulations of the present invention exhibit a substantial degree of antibody stability after storage for several months.

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Patent Owner(s)

Patent OwnerAddress
REGENERON PHARMACEUTICALS INC777 OLD SAW MILL RIVER ROAD TARRYTOWN NY 10591-6707

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dix, Daniel B Lagrangeville, US 33 578
Walsh, Scott M Sewickley, US 22 385

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