METHODS FOR TREATING CROHN'S DISEASE USING AN ANTI-IL23 ANTIBODY
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United States of America Patent
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Issued Date -
Feb 4, 2016
app pub date -
Feb 25, 2014
filing date -
Mar 15, 2013
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Abandoned
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Abstract
The invention relates to products and methods for treating Crohn's disease. The products relate to antibodies that inhibit native human IL-23 while sparing IL-12. One example describes a Phase 1, randomized, double-blind, placebo-controlled, ascending multiple dose study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of an anti-IL-23 antibody (AMG 139) in healthy subjects and subjects with mild to severe Crohn's disease.
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