LOW-GLYCERIN FORMULATIONS FOR HIV TREATMENT AND PREVENTION
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United States of America Patent
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Issued Date -
Feb 4, 2016
app pub date -
Mar 14, 2014
filing date -
Mar 15, 2013
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Abstract
The present invention relates to formulations of nucleotide reverse transcriptase inhibitors (NRTIs), preferably [2-(6-Amino-pur: in-9-yl)-1-methyl-ethoxymethy]-phosphonic acid (tenofivir, PMPA), or a physiologically functional derivative thereof, wherein the formulations contain a low level of glycerin. Human immunodeficiency vims (HIV) infection and related diseases are a major public health problem worldwide. One approach to the problem of HIV/AIDS is to reduce the risk of transmission of HIV and thus reduce the number of individuals who become newly infected.
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