ONCOLYTIC POLIOVIRUS FOR HUMAN TUMORS
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United States of America Patent
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app pub date -
Nov 21, 2013
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Nov 21, 2012
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Abstract
Human clinical use of a chimeric poliovirus construct has demonstrated excellent anti-tumor effect. The mechanism of action is believed to involve both viral oncolysis as well as immune recruitment, both of which lead to necrosis in the area of the tumor. No adverse effects have been observed.
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