METHODS OF DIAGNOSING AND TREATING FIBROSIS
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United States of America Patent
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Jan 28, 2016
app pub date -
Jul 30, 2015
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Oct 31, 2008
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Abstract
The present invention is directed to methods of diagnosing and treating a fibrotic condition in a mammalian subject. These methods involve measuring the levels of trimethylation at lysine residue 27 of histone-3 and/or measuring the expression levels of EZH2 or YY-1. Agents useful for treating fibrosis or a fibrotic condition are also disclosed.
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