PLASMONIC SUBSTRATE FOR MULTIPLEX ASSESSMENT OF TYPE 1 DIABETES
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Jan 28, 2016
app pub date -
Mar 13, 2014
filing date -
Mar 14, 2013
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Disclosed are methods and materials providing fluorescence detection of autoantibodies present in individuals who have developed or are at risk for type 1 diabetes. Provided is a plasmonic chip capable of fluorescence-enhancement of >100-fold. The fluorescent signal is generated by an anti-human antibody antibody, such as an anti-IgG antibody that is coupled to a fluorophore selected to emit at a wavelength enhanced by the plasmonic chip, for example in the NIR.
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