FLUORESCENT MARKERS AND METHODS FOR IMAGING DISEASES
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United States of America Patent
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Jan 28, 2016
app pub date -
Mar 25, 2014
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Mar 25, 2013
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Abstract
Methods and fluorescent probes that detect the presence of diseased cells such as cancer. The fluorescent probes are cloaked, turn-on probes having the fluorescence reporter released only in the presence of enzymes typically over-expressed in diseased and cancerous tissue. Probes include a fluorescent napthalimide reporter with a quinoidal moiety cloak.
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