THROMBIN SENSITIVE COAGULATION FACTOR X MOLECULES
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United States of America Patent
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app pub date -
Mar 12, 2014
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Mar 12, 2013
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Abstract
The present invention relates to thrombin sensitive coagulation Factor X (FX), as well as use thereof in medicine. In particular the invention relates to FX molecules comprising 2 to 10 amino acid modifications in the activation peptide N-terminally of the FX “IVGG” motif as well as compositions comprising such molecules and use thereof. Such molecules may be useful in connection with convenient and patient friendly treatment regimens in treatment and prophylaxis of haemophilia.
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