SEQUESTRANTS OF ADVANCED GLYCATION END PRODUCT (AGE) PRECURSORS

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United States of America Patent

APP PUB NO 20160024233A1
SERIAL NO

14776059

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Sequestrants of AGE precursors comprise amines separated by 2, 3 or 4 carbons. Sequestrants of AGE precursors can be used as pharmaceutical agents and in pharmaceutical compositions. The sequestrants of AGE precursors are particularly useful binding AGE precursors and dietary dicarbonyls in mammals in the gastrointestinal tract for the treatment of ailments such as diabetic nephropathy, chronic renal disease, atherosclerosis, stroke, cataracts, and Alzheimer's disease.

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Patent Owner(s)

Patent OwnerAddress
GENZYME CORPORATION450 WATER STREET CAMBRIDGE MA 02141

International Classification(s)

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  • 2014 Application Filing Year
  • C08F Class
  • 1886 Applications Filed
  • 1654 Patents Issued To-Date
  • 87.70 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances201420152016201720182019202020212022202320240255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
BESEV, Magnus Newton, US 8 23
DHAL, Pradeep K Westford, US 57 475
HOLMES-FARLEY, Stephen Randall Arlington, US 108 1880
MILLER, Robert J East Bridgewater, US 195 7847
PAPOULIS, Andrew T Canton, US 4 39

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  • C08F Class
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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges44511581364115411101 - 1011 - 2021 - 3031 - 4041 - 5061 - 7091 - 100100 +01002003004005006007008009001000110012001300

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