HYBRID NECROPTOSIS INHIBITORS

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United States of America Patent

SERIAL NO

14776852

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Abstract

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The present invention relates to heterocyclic compounds (e.g., compounds described by Formula (I)) and pharmaceutically acceptable salts thereof. The invention also features pharmaceutical compositions that include these compounds and their use in therapy for treating conditions in which necroptosis is likely to play a substantial role. The heterocyclic compounds described herein can also achieve improved activity and selectivity towards RIP1 and/or RIP3.

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Patent Owner(s)

Patent OwnerAddress
TUFTS UNIVERSITYBALLOU HALL MEDFORD MA 02155

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
CUNY, Gregory D Houston, US 85 957
DEGTEREV, Alexei Brookline, US 27 291
YUAN, Junying Newton, US 55 499

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