EXTENDED RELEASE PHARMACEUTICAL SOLID DOSAGE FORMULATIONS
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United States of America Patent
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Issued Date -
Jan 28, 2016
app pub date -
Mar 13, 2014
filing date -
Mar 15, 2013
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Abstract
A solid pharmaceutical dosage form, e.g., a tablet, is disclosed which comprises (a) a sustained released matrix core containing i) an at least sparingly water soluble active pharmaceutical ingredient, ii) a hydrophilic polymer, iii) an optional hydrophobic polymer, iv) an optional wax component, and v) optional diluent; and (b) a semi-permeable functional film coating surrounding the core, wherein the dosage form is substantially resistant to dose dumping when administered in the presence of ethanol. A method for making the dosage form is also provided in which the dosage form is coated with a semi-permeable coating.
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