Determination of Protein Aggregation from the Concentration Dependence of Delta G

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United States of America Patent

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14804783

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The present invention relates to, among other things, methods and systems for recognizing and characterizing protein aggregation processes at the earliest possible time and use of such new methods and systems for (1) the identification and selection of protein formulations that minimize aggregation and extend long-term stability and (2) the identification of protein variants with the lowest tendency to aggregate.

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UNCHAINED LABS6870 KOLL CENTER PARKWAY PLEASANTON CA 94566

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Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances201520162017201820192020202120222023202420250255075100

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Inventor Name Address # of filed Patents Total Citations
Brown, Richard East Falmouth, US 115 1366
Freire, Ernesto Baltimore, US 25 87
Schon, Arne Baltimore, US 5 11

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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges232940745921838355241515882101 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +0250500750100012501500175020002250250027503000325035003750400042504500

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