CHIMERIC POLYPEPTIDES, POLYNUCLEOTIDES ENCODING SAME, CELLS EXPRESSING SAME AND METHODS OF PRODUCING SAME
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United States of America Patent
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Jan 21, 2016
app pub date -
Mar 6, 2014
filing date -
Mar 6, 2013
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Abstract
A plant produced chimeric polypeptide is provided. The plant produced chimeric polypeptide comprising:
- (i) a first domain which comprises a TNF Alpha binding domain of a TNF receptor, and(ii) a second domain which comprises an Fc domain of an immunoglobulin, wherein the first domain and the second domain are N-terminally to C-terminally respectively sequentially translationally fused and wherein the chimeric polypeptide specifically binds TNF Alpha.
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