Exo Olefin-Containing Nuclear Transport Modulators and Uses Thereof
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United States of America Patent
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Issued Date -
Jan 21, 2016
app pub date -
Mar 14, 2014
filing date -
Mar 15, 2013
priority date (Note) -
Abandoned
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Abstract
The invention generally relates to nuclear transport modulators, e.g., CRM1 inhibitors, and, more particularly, to a compound represented by structural formula (I), or a pharmaceutically acceptable salt thereof, wherein the variables are as defined and described herein. The invention also includes the synthesis and use of a compound of structural formula I, or a pharmaceutically acceptable salt or composition thereof, e.g., in the treatment, modulation and/or prevention of physiological conditions associated with CRM1 activity.
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