METHODS FOR PHOSPHINE OXIDE REDUCTION IN CATALYTIC WITTIG REACTIONS

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United States of America Patent

SERIAL NO

14775931

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Abstract

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A method for increasing the rate of phosphine oxide reduction, preferably during a Wittig reaction comprising use of an acid additive is provided. A room temperature catalytic Wittig reaction (CWR) the rate of reduction of the phosphine oxide is increased due to the addition of the acid additive is described. Furthermore, the extension of the CWR to semi-stabilized and non-stabilized ylides has been accomplished by utilization of a masked base and/or ylide-tuning.

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Patent Owner(s)

Patent OwnerAddress
DUBLIN CITY UNIVERSITYGLASNEVIN DUBLIN D9

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  • 2014 Application Filing Year
  • C07F Class
  • 1196 Applications Filed
  • 979 Patents Issued To-Date
  • 81.86 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances20142015201620172018201920202021202220230255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
O'BRIEN, Christopher Runcorn, GB 33 170

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  • C07F Class
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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges1883243357411201 - 1011 - 2021 - 3031 - 4041 - 5071 - 8081 - 90100 +020406080100120140160180200220240260280300320340360

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