A METHOD FOR PREPARING SILICA-COATED MAGNETIC BEAD
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United States of America Patent
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Jan 14, 2016
app pub date -
Jul 9, 2014
filing date -
Jul 9, 2014
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Abstract
The present invention relates to a method of preparing a sedimentation adjustment silica-coated magnetic bead, comprising the following steps: (1) preparing a magnetic core; (2) adding various ratio of silica coating material to coat the magnetic core with silica forming a silica-coated magnetic bead; and (3) washing the silica-coated magnetic bead sequentially by an alcoholic solvent and water. The present invention also relates to a silica-coated magnetic bead prepared by the above method, comprising a magnetic core and a tunable silica layer, wherein the thickness of the tunable silica layer is ranging from 0.77-2.31 μm.
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