NOVEL INSULIN ANALOG AND USE THEREOF
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United States of America Patent
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Jan 14, 2016
app pub date -
Feb 26, 2014
filing date -
Feb 26, 2013
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Abstract
The present invention relates to an insulin analog that has a reduced insulin titer and a reduced insulin receptor binding affinity compared to the native form for the purpose of increasing the blood half-life of insulin, a conjugate prepared by linking the insulin analog and a carrier, a long-acting formulation including the conjugate, and a method for preparing the conjugate.
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