METHODS OF TREATMENT OF CANCER

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United States of America Patent

SERIAL NO

14373991

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Abstract

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The present invention provides a method of treating cancer with a proteasome inhibitor. The invention also provides a method of treating a patient with cancer based on elevated expression levels of NFκB, as measured by a H-score of the patients tumor sample using a NFκB p65 IHC assay. The invention also provides a method of determining whether to treat a patient with a proteasome inhibitor based on the level of NFκB p65 in the patient's tumor sample.

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Patent Owner(s)

Patent OwnerAddress
MILLENNIUM PHARMACEUTICALS INC75 SIDNEY STREET CAMBRIDGE MA 02139

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
BLAKEMORE, Stephen J Littleton, US 12 22
DI, BACCO Alessandra M Newton, US 5 2
MULLIGAN, George J Lexington, US 12 92

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