METHODS OF TREATING IPEX SYNDROME USING TOXIN-BASED PHARMACEUTICAL COMPOSITIONS
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United States of America Patent
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Issued Date -
Jan 7, 2016
app pub date -
Mar 5, 2014
filing date -
Mar 5, 2013
priority date (Note) -
Abandoned
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Abstract
Disclosed herein are methods of treating immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) comprising administering a toxin-based therapeutic peptide, such as an ShK-based peptide. The peptide can include an acid or amide at the C-terminus and/or the peptide can be attached to an organic or inorganic chemical entity that has an anionic charge.
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