ZWITTERION SURFACE MODIFICATIONS FOR CONTINUOUS SENSORS
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United States of America Patent
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app pub date -
Aug 31, 2015
filing date -
Sep 28, 2012
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Abandoned
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Abstract
Devices are provided for measurement of an analyte concentration, e.g., glucose in a host. The device can include a sensor configured to generate a signal associated with a concentration of an analyte; and a sensing membrane located over the sensor. The sensing membrane comprises a diffusion resistance domain configured to control a flux of the analyte therethrough. The diffusion resistance domain comprises one or more zwitterionic compounds and a base polymer comprising both hydrophilic and hydrophobic regions.
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