ANTIMICROBIAL METHOD BY BLOCKING MANNITOL METABOLISM AND ANTIMICROBIAL COMPOSITION CONTAINING MANNITOL METABOLIC INHIBITOR
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United States of America Patent
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Dec 24, 2015
app pub date -
Oct 31, 2014
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Jun 23, 2014
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Abstract
The present invention relates to an antimicrobial method of killing bacteria having a mannitol metabolic pathway by inhibition of a mannitol metabolism, a method of screening a mannitol metabolic inhibitor, and an antimicrobial composition and cosmetic material containing a mannitol metabolic inhibitor. More particularly, the present invention relates to an antimicrobial method targeted at mannitol dehydrogenase such as mannitol-1-phosphate-5-dehydrogenase (M1PDH), a method of screening an inhibitor, and a composition. Therefore, the antimicrobial method, antimicrobial composition, and cosmetic material which solve a problem of antibiotic resistance and have an excellent antimicrobial effect may be provided.
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