ASSESSING SUSCEPTIBILITY TO CARDIAC INTERVENTION, SUSCEPTIBILITY TO THERAPY FOR HEART FAILURE, RISK OF MORTALITY OR FURTHER CARDIOVASCULAR EVENTS, AND RISK OF SUBSEQUENT PULMONARY EMBOLISM IN RELEVANT PATIENTS BASED ON DETERMINATIONS OF GDF-15, NATRIURETIC PEPTIDE, CARDIAC TROPONIN OR COMBINATIONS THEREOF

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United States of America Patent

SERIAL NO

14617927

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Abstract

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The present invention relates to a method of identifying a subject being susceptible to a cardiac intervention based on the determination of GDF-15 in a sample of a subject in need of a cardiac intervention. Moreover, the present invention pertains to a method for predicting the risk of mortality or a further acute cardiovascular event for a subject suffering from a cardiovascular complication based on the determination of GDF-15 and a natriuretic peptide and/or a cardiac troponin in a sample the said subject. Also encompassed by the present invention, are devices and kits for carrying out the aforementioned methods.

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Patent Owner(s)

Patent OwnerAddress
MEDIZINISCHE HOCHSCHULE HANNOVERCARL-NEUBERG-STRASSE 1 HANNOVER 30625

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Drexler, Helmut Hannover, DE 3 28
Kempf, Tibor Hannover, DE 3 28
Wallentin, Lars Uppsala, SE 6 38
Wollert, Kai C Hannover, DE 3 28

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