NICOTINAMIDES AS JAK KINASE MODULATORS
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United States of America Patent
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Issued Date -
Dec 10, 2015
app pub date -
Jun 29, 2015
filing date -
Nov 1, 2010
priority date (Note) -
Abandoned
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Abstract
The present invention is directed to compounds of formula I and pharmaceutically acceptable salts, esters, and prodrugs thereof which are inhibitors of JAK kinase. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition JAK kinase activity, methods of inhibition the platelet aggregation, and methods to prevent or treat a number of conditions mediated at least in part by JAK kinase activity, such as undesired thrombosis and Non Hodgkin's Lymphoma.
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