iPS/ES CELL-SPECIFIC ANTIBODY HAVING CYTOTOXICITY TO TARGET CELLS AND USE THEREOF
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United States of America Patent
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Issued Date -
Dec 3, 2015
app pub date -
Dec 20, 2013
filing date -
Dec 21, 2012
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Abandoned
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Abstract
The present invention provides a monoclonal antibody that recognizes a lipid substance on an iPS cell surface and an ES cell surface as an epitope, and does not recognize EC cells, the antibody having a cytotoxic activity against a target cell, a method of producing a uniform differentiated cell population free of an undifferentiated cell, including contacting a cell population differentiated from an iPS or ES cell with the above antibody, and recovering viable cells, an agent for a cell transplantation therapy, containing a differentiated cell population obtained by the method, and the like.
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