VACCINE FOR HPV INFECTION AND/OR HEPATITIS B COMPRISING HPV/HBS CHIMERIC PROTEIN AS ACTIVE INGREDIENT
Number of patents in Portfolio can not be more than 2000
United States of America Patent
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N/A
Issued Date -
Dec 3, 2015
app pub date -
Nov 28, 2013
filing date -
Dec 25, 2012
priority date (Note) -
Published
status (Latency Note)
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Abstract
A chimeric protein of HPV-L2 peptide and HBs protein wherein the HPV-L2 peptide is (1) a peptide consisting of the core sequence region of 20 amino acid residues, (2) a peptide inside the core sequence region comprising 6 amino acid residues Gly-Gly-Leu-Gly-Ile-Gly or (3) a peptide consisting of 70 or less amino acid residues obtained by adding an amino acid sequence derived from HPV L2 protein at the N-terminal and/or the C-terminal of the core sequence region; and a vaccine for HPV infection and/or hepatitis B comprising the chimeric protein as an active ingredient. A vaccine comprising the chimeric protein of the present invention is the one that has an increased expression level in a host, an enhanced immune ability (early antibody induction) and a broader spectrum effective for a number of HPV types.
First Claim
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Family

- 15 United States
- 10 France
- 8 Japan
- 7 China
- 5 Korea
- 2 Other
Patent Owner(s)
Patent Owner | Address | |
---|---|---|
THE CHEMO-SERO-THERAPEUTIC RESEARCH INSTITUTE | KUMAMOTO JAPAN KUMAMOTO-SHI KUMAMOTO | |
JAPAN AS REPRESENTED BY DIRECTOR GENERAL OF NATIONAL INSTITUTE OF INFECTIOUS DISEASES | TOYAMA 1-23-1 SHINJUKU-KU TOKYO 1628640 ?1628640 |
International Classification(s)
Inventor(s)
Inventor Name | Address | # of filed Patents | Total Citations |
---|---|---|---|
IMAMURA, Takashi | Kikuchi-gun, Kumamoto, JP | 82 | 565 |
# of filed Patents : 82 Total Citations : 565 | |||
KANDA, Tadahito | Setagaya-ku, Tokyo, JP | 4 | 8 |
# of filed Patents : 4 Total Citations : 8 | |||
MORI, Seiichiro | Kodaira-shi, Tokyo, JP | 57 | 713 |
# of filed Patents : 57 Total Citations : 713 | |||
SAKAGUCHI, Masashi | Kumamoto-shi, Kumamoto, JP | 56 | 386 |
# of filed Patents : 56 Total Citations : 386 | |||
YONEMURA, Hiroshi | Kumamoto-shi, Kumamoto, JP | 11 | 86 |
# of filed Patents : 11 Total Citations : 86 |
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Patent Citation Ranking
- 3 Citation Count
- C07K Class
- 42.08 % this patent is cited more than
- 10 Age
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Maintenance Fees
Fee | Large entity fee | small entity fee | micro entity fee | due date |
---|---|---|---|---|
11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | Jun 3, 2027 |
Fee | Large entity fee | small entity fee | micro entity fee |
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Surcharge - 11.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
Surcharge after expiration - Late payment is unintentional | $1,640.00 | $820.00 | $410.00 |
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