BICYCLIC PYRIMIDONE COMPOUNDS AS INHIBITORS OF LP-PLA2
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United States of America Patent
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Dec 3, 2015
app pub date -
Jan 23, 2014
filing date -
Jan 25, 2013
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Abstract
The present invention relates to novel pyrimido[1,6-a]pyrimidin-6(2H)-one compounds that inhibit Lp-PLA2 activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease.
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