BIMODAL FLUOROPHORE-LABELED LIPOSOMES AND ASSOCIATED METHODS AND SYSTEMS
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United States of America Patent
Stats
-
N/A
Issued Date -
Dec 3, 2015
app pub date -
May 27, 2015
filing date -
May 28, 2014
priority date (Note) -
Published
status (Latency Note)
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Abstract
Described herein is a non-invasive quantitative positron emission tomography (PET) nanoreporter technology that allows personalized therapeutic outcome prediction. In a breast cancer mouse model, it was demonstrated that co-injecting Doxil and a Zirconium-89 nanoreporter (89Zr-NRep) enabled highly precise doxorubicin (DOX) quantification. Imaging 89Zr-NRep via PET revealed remarkable Doxil accumulation heterogeneity independent of tumor size.
First Claim
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Family

- 15 United States
- 10 France
- 8 Japan
- 7 China
- 5 Korea
- 2 Other
Patent Owner(s)
Patent Owner | Address | |
---|---|---|
ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI | ONE GUSTAVE L LEVY PLACE NEW YORK NY 10029 |
International Classification(s)

- 2015 Application Filing Year
- A61K Class
- 16157 Applications Filed
- 11882 Patents Issued To-Date
- 73.55 % Issued To-Date
Inventor(s)
Inventor Name | Address | # of filed Patents | Total Citations |
---|---|---|---|
Fayad, Zahi A | New York, US | 11 | 164 |
# of filed Patents : 11 Total Citations : 164 | |||
Lewis, Jason S | New York, US | 24 | 107 |
# of filed Patents : 24 Total Citations : 107 | |||
Mulder, Willem JM | New York, US | 3 | 1 |
# of filed Patents : 3 Total Citations : 1 | |||
Perez-Medina, Carlos | New York, US | 5 | 4 |
# of filed Patents : 5 Total Citations : 4 | |||
Reiner, Thomas | New York, US | 34 | 237 |
# of filed Patents : 34 Total Citations : 237 |
Cited Art Landscape
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Patent Citation Ranking
- 1 Citation Count
- A61K Class
- 31.06 % this patent is cited more than
- 10 Age
Forward Cite Landscape
- No Forward Cites to Display

Maintenance Fees
Fee | Large entity fee | small entity fee | micro entity fee | due date |
---|---|---|---|---|
11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | Jun 3, 2027 |
Fee | Large entity fee | small entity fee | micro entity fee |
---|---|---|---|
Surcharge - 11.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
Surcharge after expiration - Late payment is unintentional | $1,640.00 | $820.00 | $410.00 |
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