HMGB1-BINDING BEADS AND USES THEREOF
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United States of America Patent
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Nov 26, 2015
app pub date -
Jan 9, 2014
filing date -
Jan 9, 2013
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Abstract
Disclosed are therapeutic beads comprising agents, such as nucleic acids, that bind to high mobility group box 1 (HMGB1) and methods of treating subjects with conditions that would benefit from reducing the deleterious effects of HMGB1, such as inflammatory bowel diseases, comprising administering the beads to the gastrointestinal tract of the subjects.
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