COMPOSITION FOR TREATING EPSTEIN-BARR VIRUS INFECTION, COMPRISING EPSTEIN-BARR VIRUS MICRO RNA INHIBITOR
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United States of America Patent
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Issued Date -
Nov 19, 2015
app pub date -
May 1, 2015
filing date -
May 16, 2014
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Abandoned
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Abstract
Provided is a composition comprising an Epstein-Barr virus microRNA inhibitor for treating Epstein-Barr virus infection, and a method using Epstein-Barr virus microRNA for screening a therapeutic agent for treating Epstein-Barr virus infection. The provided composition enables one to induce the lytic cycle of EBV such that EBV-infected cells are destroyed by a host immune system. Therefore, the composition can be effectively used for the prevention or treatment of diseases, including various cancers, caused by EBV infection. Moreover, the provided method enables one to screen a therapeutic agent having excellent antiviral effect for treating Epstein-Barr virus infection by inducing Epstein-Barr virus lytic cycle.
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