REPLICATIVE MINICIRCLE VECTORS WITH IMPROVED EXPRESSION
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Nov 12, 2015
app pub date -
Mar 14, 2013
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Nov 19, 2012
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Abstract
The present invention relates to the production and use of covalently closed circular (ccc) recombinant DNA molecules such as plasmids, cosmids, bacterial artificial chromosomes (BACs), bacteriophages, viral vectors and hybrids thereof, and more particularly to vector modifications that improve expression of said DNA molecules.
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