OSSIFICATION-INDUCING COMPOSITIONS AND METHODS OF USE THEREOF
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United States of America Patent
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Issued Date -
Nov 12, 2015
app pub date -
Dec 13, 2013
filing date -
Dec 13, 2012
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Abstract
Mesenchymal stem cells (MSCs) and uses thereof are provided. MSCs for inducing ossification and enhancing bone and/qr cartilage repair in a patient in need thereof are also provided. The method and compositions combine MSCs, at least one bone regeneration protein, such as bone morphogenetic protein (e.g. BMP-2), optionally in combination with additional cell growth factors including the components of a cell growth medium, further in combination with a biomaterial for delivery of the cells to the repair site in the patient are also provided.
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