Non-replicating virus-derived particles and uses thereof
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United States of America Patent
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Sep 7, 2021
Grant Date -
Nov 12, 2015
app pub date -
Dec 20, 2013
filing date -
Dec 21, 2012
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Abstract
There is described herein a non-replicating Rhabdovirus-derived particle that lacks the ability to spread between cells while having tropism against immortalized cells. The non-replicating Rhabdovirus-derived particle may have cytolytic tropism against immortalized cells. There is also described a non-replicating Rhabdovirus-derived particle that lacks the ability to spread between cells but has innate and/or adaptive immune-stimulating properties.
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