FORMULATIONS AND METHODS OF TREATING ALZHEIMER'S DISEASE AND OTHER PROTEINOPATHIES BY COMBINATION THERAPY

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United States of America Patent

SERIAL NO

14707033

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Abstract

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Administration of a 1-phenylalkanecarboxylic acid before, after, or a concurrently with a therapeutically effective amount of one or more of the following: (1) β-amyloid peptides level reducers, (2) pathogenic level tau reducers, (3) microtubule stabilizers, (4) agents capable or removing atherosclerotic plaques, (5) agents that lower circulating levels of β-amyloid and tau, (6) modulators of autophagy, (7) neurotransmitter levels regulators, (8) GABA(A) α5 Receptor Antagonists, and (9) additional agents that help maintain and/or restore cognitive function and functional deficits of AD, and/or slow down decline in cognitive functions and functional deficits in AD, is useful for prevention or therapeutical treatment of proteinopathies and/or neurodegenerative diseases.

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Patent Owner(s)

Patent OwnerAddress
CHIESI FARMACEUTICI S P AVIA PALERMO 26/A PARMA 43122

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
CHAIN, Daniel Parma, IT 7 10
IMBIMBO, Bruno Pietro Parma, IT 18 35

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