PROTEIN ENRICHED MICROVESICLES AND METHODS OF MAKING AND USING THE SAME
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United States of America Patent
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Nov 5, 2015
app pub date -
Jun 11, 2015
filing date -
Jun 11, 2013
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Abstract
The present invention relates to a microvesicle comprising: (i) a membrane-associated protein comprising at least one first dimerization domain, (ii) a carrier protein comprising at least one second dimerization domain, and (iii) a solute that binds to the carrier protein, wherein the solute is selected from the group of: DNA, RNA, protein, carbohydrate, ribosomes, mitochondria, and small molecules. Also provided are cells, reagents and kits that find use in making the microvesicles, as well as methods of using the microvesicles, e.g., in research and therapeutic applications
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