Polysialic acid derivatives

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United States of America Patent

PATENT NO 9920137
SERIAL NO

14791468

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Abstract

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A polysialic acid compound is reacted with a hetero-bifunctional reagent to introduce a pendant functional group for site-specific conjugation to sulfhydryl groups, for instance side chains of cysteine units in drugs, drug delivery systems, proteins or peptides. The functional group is, for instance, an N-maleimide group.

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Patent Owner(s)

Patent OwnerAddress
LIPOXEN TECHNOLOGIES LIMITEDLONDON BIOSCIENCE INNOVATION CENTER 2 ROYAL COLLEGE STREET LONDON NW1 0NH

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gregoriadis, Gregory London, GB 52 366
Hreczuk-Hirst, Dale Howard London, GB 8 59
Jain, Sanjay London, GB 115 1620
Laing, Peter London, GB 67 450
Papaioannou, Ioannis London, GB 24 79

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